The global cartilage repair market size is expected to reach USD 2,268.8 Million in 2028 and register a revenue CAGR of 14.5% during the forecast period. Growing number of sports events worldwide, rising interest of people of young generation in sports, and increasing incidence of sports-related injuries are factors driving market revenue growth. Joints, especially knee joints, possess an intricate structure, making it prone to injuries, mainly for athletes. Certain kinds of sports such as football, running, lacrosse, basketball, or skiing, place intense strain on knee joints and hence increase risks associated with knee injuries, resulting from extreme movements intrinsic to the sport such as abrupt stops, twists, and turns. Overuse of knee joints while frequent playing can lead to trauma resulting from blunt force or intense training and can cause injury to knees, and in turn, create need for cartilage repair surgery.
Revenue growth of the global cartilage repair market can be attributed to rising incidence of on-road accidents leading to knee injuries that can have severe consequences on an individual. Knee injuries usually result from sudden external force on knees and can occur in several ways on basis of nature of accident such as side-impact, rear-ender, or rollover. These kinds of incidences can result in need for cartilage repair surgery for recovery from joint damage, and in turn drive market revenue growth.
Additionally, cartilage has poor blood supply as compared to other body tissues, and therefore has limited potential to heal itself or to support donor cartilage. It is a connective tissue found in various parts of the body, especially joints. Major players are investing for R&D of better solutions for cartilage regeneration and repair, as degeneration of meniscus (fibrocartilage) tissue affects numerous patients worldwide. Researchers have recently developed 3D technology that helps to bio-print a 3D hybrid tissue constructed for regenerating cartilage by using specialized bio-inks. These inks comprise hydrogels to develop a new formulation that creates a cell-friendly microenvironment and provides structural integrity.
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Market Dynamics:
Driver: Rising incidence of joint injuries
Cartilage repair market revenue growth is due to rising incidence of joint injuries, mostly due to obesity, accidents, playing sports, and some other medical conditions/ diseases. In most cases, patients of cartilage damage comprise young population suffering from knee joint injuries such as meniscal or ligament tears, resulting in need for knee cartilage repair surgery. Healing of damaged cartilage is a slow process, and procedures such as autologous chondrocytes implantation and cell-based cartilage resurfacing are employed to stimulate growth of new cartilage in joints. Cartilage repair and restoration provides significant relief from pain and allow better joint movement, and also helps to delay or prevent onset of arthritis.
Restraint: High cost of cartilage repair surgeries
High cost associated with cartilage repair surgeries could hamper market revenue growth over forecast period. Cost prohibitive surgeries can discourage patients form opting for knee cartilage repair procedures and instead opt for relatively cheaper treatments such as therapies to strengthen muscles helping in knee stabilization. In addition, dearth of skilled surgeons who are capable of performing knee cartilage repair surgeries can restrain market revenue growth.
COVID-19 Analysis:
COVID-19 had a significant impact on the cartilage repair market growth. During the pandemic, hospital visits and patient admissions reduced due to rising number of COVID-19 cases in various hospitals and lockdown restrictions, resulting in substantial drop in cartilage repair surgeries. However, currently, global market revenue is growing at a rapid rate as restrictions have been lifted, and sports events are being held normally as scheduled, and healthcare facilities are functioning normally.
Treatment modality Insights:
Based on treatment modality, the global cartilage repair market is segmented into cell based, non-cell based, and others. The cell-based segment accounted for largest revenue share in 2020. Cell-based treatment is a kind of biological treatment, which encompasses process of putting new cells with damaged tissues for treatment of age-related or degenerative diseases. Cartilage is the most appropriate tissue for regeneration purpose. The primary purpose of a cell-based treatment for cartilage imperfections is to repair injured joint surfaces using healthy tissue that can endure the stresses and strains caused by joint loading.
Application Insights:
Based on application, the global cartilage repair market is segmented into hyaline, fibrocartilage, elastic cartilage, and others. The hyaline segment accounted for largest revenue share in 2020. Hyaline cartilage has a high composition of collagen, a protein present in connective tissues, and is beneficial in holding the joints together. This cartilage offers support and flexibility to various body parts. It is present in ears, nose, larynx and trachea in the respiratory system, and other body parts to give shape as well as flexibility. Hyaline cartilage, when present in the bone’s articular surfaces, is known as articular cartilage, which performs the role of a shock absorber, and lessens friction in the bone joints.
Fibrocartilage segment accounted for significantly large revenue share in 2020. Fibrocartilage functions as a joint stabilizer and shock absorber by providing cushion layer in knee joints involved in bearing of strain and load. Fibrocartilage in knee joints is much more responsive to joint instability and hence in many cases act as an indicator of pending degeneration of cartilage.
Treatment Type Insights:
Based on treatment type, the global cartilage repair market is segmented into palliative, intrinsic repair stimulus, and others. Intrinsic repair stimulus segment accounted for considerably large revenue share in 2020. Intrinsic repair stimulus comprises microfracture and drilling techniques to repair cartilage tissue. Microfracture surgery creates small perforations in subchondral bone surface and enables more vascular bones to access the bone surface layer and supply blood, thereby stimulating new cartilage growth.
End Use Insights:
Based on end use, the global cartilage repair market is segmented into hospitals, clinics, ambulatory surgical centers, and others. The hospitals segment accounted for largest revenue share in 2020. Factors such as well-resourced operating rooms, higher purchasing power, availability of highly skilled healthcare professionals, and better health insurance coverage for hospital-based healthcare services from many private and group insurance providers, are factors driving revenue growth of the hospital segment.
Regional Insights:
North America accounted for largest revenue share in 2020, owing to increasing use of advanced technologies in the healthcare sector, rising prevalence of obesity, increasing investments in R&D of cutting-edge cartilage repair procedures, and increasing healthcare spending. Additionally, presence of various major players, such as Stryker Corporation and Zimmer Biomet, is supporting revenue growth of the market in this region.
Cartilage repair market in Asia Pacific is expected to register fastest revenue CAGR over forecast period, attributed to growing inclination for sports among children and youths in countries such China, Japan, and India in the region, increasing rate of accidents, and rising emphasis on improving healthcare infrastructure. In addition, rising disposable income and growing geriatric population are supporting revenue growth of the Asia Pacific market.
Competitive Landscape
Companies profiled in the global market report includes Zimmer Biomet, Stryker Corporation, DePuy Synthes, Smith & Nephew PLC, Vericel Corporation, Osiris Therapeutics Inc., B. Braun Melsungen AG, Anika Therapeutics Inc., Arthrex Inc., and Collagen Solutions PLC.
Initiatives taken by market players are driving growth of the market, for instance:
In April 2020, Eisai Co., Ltd. entered into a co-development and marketing agreement with Seikagaku Corporation for SI-613, which is a therapeutic agent for use in osteoarthritis treatment. SI-613 consists of diclofenac conjugated sodium hyaluronate. As per the agreement, firms would jointly develop SI-613 in China.
In April 2018, Stryker and AlloSource made an announcement about launch of a cryopreserved osteochondral allograft called ProChondrixCR. It is intended to offer better solutions to patients requiring articular cartilage repair.
Segments Covered in the Report
This report offers historical data and forecasts revenue growth at a global, regional, and country level, and provides analysis of the market trends in each of the sub-segments from 2019 to 2030. For this study, Reports and Data has segmented the global cartilage repair market based on treatment modality, application, treatment type, end use, and region:
Cartilage Repair Market Report Scope
Segments covered By Treatment Modality Outlook, Application Outlook, Treatment Type Outlook, Regional Outlook
By Treatment Modality Outlook
Cell-Based
Chondrocyte Transplantation
Growth Factor Technology
Non-Cell-Based
Tissue Scaffolds
Cell-Free Composites
Others
By Application Outlook
Hyaline
Fibrocartilage
Elastic Cartilage
Others
By Treatment Type Outlook
Palliative
Viscosupplementation
Debridement & Lavage
Intrinsic Repair Stimulus
Other
End Use Outlook
Hospital
Clinics
Ambulatory Surgical Centers
Others
Regional scope
North America
Europe
Asia Pacific
Latin America
Middle East & Africa
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