The global tangential flow filtration market size was significantly robust in 2022 and is expected to register a steady revenue CAGR over the forecast period. Key factors providing impetus to market revenue growth are increasing investment in pharmaceutical sector, rising acceptance of single-use technologies, and various benefits associated with tangential flow filtering.
Tangential Flow Filtration (TFT) is a type of technique used for purifying and separating biomolecules. Tangential flow filtration, also known as cross-flow filtering, is critical in both upstream as well as downstream processes conducted in bio-manufacturing industries TFT concentrates and desalts sample solutions with volumes ranging from a few milliliters to thousands of litres. Besides, it is utilized in separation and purification of nucleic acids, antibodies, and recombinant proteins. It provides a number of benefits, including ease of scaling up and down, ease of setup and operation, and time and money savings. Immunology, protein chemistry, biology, biochemistry, and microbiology are few of biological fields where it is used. The solution is delivered tangentially at surface of the filter, with pressure differential directing constituents smaller than pores through the filter.
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Major Factors Driving Growth Of The Global Tangential Flow Filtration Market:
Revenue growth of the global tangential flow filtration market is significantly driven rapid development of pharmaceutical sector, increasing in biologics manufacturing, and technological advancements. TFT has several advantages, including ease of set-up and operation, easy scaling-up and scaling-down, and time and money savings, which has led to its widespread use in various sectors. Rising adoption of single-use technologies and TFT in biopharmaceutical companies due to their effectiveness in a variety of applications, including biomolecule separation and purification, bioprocessing downstream, and upstream harvesting are some key factors positively contributing to market growth.
Factors Restraining Growth Of The Global Tangential Flow Filtration Market:
The global tangential flow filtration market growth is substantially hampered by several unfavorable factors. Presence of competing technologies such as pre-coat filtration, centrifugation, and direct flow filtration as well as high setup costs and easy availability of product replacements, are factors expected to negatively impact market revenue growth over the forecast period. Furthermore, stringent rules and regulations imposed by government globally and various complications generated by interaction of charged excipients and proteins are other factors expected to cause a slow-down in market growth.
Opportunities For Players Operating In The Global Tangential Flow Filtration Market:
Focus on developing filtration systems that are available at lower cost and need for more advanced designs and safety features are some key factors expected to continue to open up lucrative business opportunities for major players and new entrants in the market. Furthermore, rapid advancements in single-use technologies are expected to support market growth going ahead.
Global Tangential Flow Filtration Market Revenue Led By Product Type Segment:
Based on product type, the TFF system segment is expected to reach the highest revenue share over the forecast period. Various benefits of single-use TFF technologies, such as less cross-contamination, more flexibility, and reduced process time are driving demand for this segment. In addition, other advantages of these completely automated single-use systems include reduced validation, lower capital costs, and fewer cleaning requirements. Furthermore, as single-use TFF technology improves, biologics manufacturing landscape is projected to rearrange itself, allowing industry to embrace simpler and disposable systems.
Global Tangential Flow Filtration Market Led By Technology Type Segment:
Based on technology type, the microfiltration segment is expected to reach the highest revenue share over the forecast period. This is attributed to rising demand for cell separation. This approach is widely used in production of antibiotics for harvesting cells in upstream bioprocessing and for the recovery and purification of biomass.
Global Tangential Flow Filtration Market Led By Application:
Based on application, the viral vector purification segment is expected to dominate all other segments in terms of revenue generation over the forecast period. This is attributed to rising focus on adopting advanced techniques
North America Accounts For Largest Revenue Share In Global Tangential Flow Filtration Market:
Among regional markets, North America emerged as the largest market for tangential flow filtration in 2020, with the highest revenue share. Revenue growth in the North America market is mainly attributed to the region’s thriving pharmaceutical and biopharmaceutical industry, presence of established market players, and rising investments in research and development activities to introduce modern technologies.
Asia Pacific Continues To Lead In Terms Of Revenue CAGR:
The Asia Pacific tangential flow filtration market is expected to register the fastest growth in CAGR over the forecast period. This is attributed to rapid development of contract manufacturing base in countries such as China, Japan, and India. Several small and medium-scale companies in APAC have received US Food and Drug Administration (FDA) permission for their operations and have completed GMP certification, resulting in increased demand for TFT solutions.
Major Companies Profiled In The Report:
- Danaher Corporation
- Merck Millipore
- Sartorius Stedim Biotech S.A.
- Parker Hannifin Corporation
- GE Healthcare
- Alfa Laval AB
- Koch Membrane Systems, Inc.
- Spectrum Laboratories, Inc.
Strategies And Objectives Of Major Companies:
Global market is led by Merck Millipore (US). Tangential flow filtering products are widely available around the world. Strong product portfolio, brand recognition, and high demand for bioprocess technologies, notably TFF, from bioprocessing business units, particularly in Asia Pacific and North America are some factors that provide lucrative opportunities for companies.
- In February 2019, Danaher Corporation purchased GE Healthcare\’s BioPharma unit, which specializes in advanced TFF systems. Owing to intrinsic relationship between their core product groups, this transaction gives Danaher Corporation with substantial market share.
What Our Report Provides And Why Our Offering Is Better:
This report offers historical data points and forecasts and revenue growth at a global, regional, and country level, and provides analysis, industry trends, and consumption pattern details for each region, major country, and segment from 2023 to 2032. The global market report includes industry trends, drivers, restraints, opportunities, threats, market strategies, segment revenue, and market share contribution by each regional and country market. In addition, the report offers industry analysis and competitive landscape, company financials, and impact analysis. The report includes a detailed view of the global market, along with changing dynamics and trends, scenarios, detailed market and regional segmentation, regional landscape, analysis and evaluation, major investments, product offerings, product launches, and details of historical, current, and projected revenues.
Detailed Segmentation In Our Report:
For the purpose of this report, the global tangential flow filtration market is segmented on the basis of product type, technique, material type, application and region:
Product Type Outlook (Revenue, USD Billion; 2023-2032)
- TFF System
- Membrane Filter
Technique Type Outlook (Revenue, USD Billion; 2023-2032)
Material Type Outlook (Revenue, USD Billion; 2023-2032)
- PES/PE Membrane
- Regenerated Cellulose
Application Outlook (Revenue, USD Billion; 2023-2032)
- Viral Vector Purification
End-Use Outlook (Revenue, USD Billion; 2023-2032)
- Pharmaceutical and Biotechnological Companies
- Academic & Research Institutes
- Contract Research Organizations
Region Outlook (Revenue, USD Billion; 2023-2032)
- North America
- Rest of Europe
- Asia Pacific
- South Korea
- Rest of Asia Pacific
- Latin America
- Rest of Latin America
- Middle East & Africa
- Saudi Arabia
- South Africa
- Rest of Middle East & Africa
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